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17

Compounds

Cat No. Product Name Synonyms Targets
T12774 RSV-IN-1 RSV
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM.
T61343 RSV/IAV-IN-1
RSV/IAV-IN-1 (compound 14e) is a potent dual inhibitor of RSV/IAV with lower cytotoxicity compared to Ribavirin, suggesting promising potential for researching RSV and/or IAV infections [1].
T61217 RSV-IN-3
RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1].
T60910 RSV-IN-4
RSV-IN-4 (Compound 2) has anti-RSV activity with EC50 of 11.76 μM. RSV-IN-4 is a respiratory syncytial virus (RSV) and influenza virus A (IAV) dual inhibitor [1].
T61704 RSV-IN-6
RSV-IN-6 (Compound 53) is a specific agent that effectively inhibits the respiratory syncytial virus (RSV) by targeting the M2-1 protein. It shows strong potency, with EC50 values of 4.4 μM and 1.3 μM against RSV-A and R...
T79217 RSV L-protein-IN-2 RSV
RSV L-protein-IN-2 (Compound A), a noncompetitive inhibitor of the RSV polymerase (IC50: 4.5 μM), exhibits antiviral activity against long RSV strains (EC50: 1.3 μM) [1].
T61291 RSV/IAV-IN-2
RSV/IAV-IN-2 (compound 14c) represents a powerful dual inhibitor of RSV/IAV, exhibiting lower cytotoxicity compared to the clinical drug Ribavirin. It holds promise for the research of RSV and/or IAV infections [1].
T79219 RSV L-protein-IN-3 RSV
RSV L-protein-IN-3 is an inhibitor of the wild-type RSV polymerase, exhibiting an IC50 of 10.4 μM and an EC50 of 2.1 μM (against RSV), and possesses lower cytotoxicity compared to the clinical agent Ribavirin [1].
T79220 RSV L-protein-IN-4 RSV
RSV L-protein-IN-4 (Compound C) is a noncompetitive inhibitor of the RSV polymerase with an IC50 of 0.88 μM. It demonstrates potent antiviral activity against RSV strains, with an EC50 of 0.25 μM [1].
T73370 RSV-IN-7
RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) .
T76752 Motavizumab
Motavizumab (MEDI-524) is a monoclonal antibody targeting the respiratory syncytial virus (RSV). It is utilized in research focused on RSV infections in high-risk infants [1].
T77027 Gontivimab
Gontivimab (ALX-0171; VR-465), a potent anti-RSV prefusion F protein nanobody, exhibits antiviral activity by reducing the RSV load in the nose and lung, with a dissociation constant (K D) of 0.113 nM [1].
T79221 RSV L-protein-IN-5 RSV
RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM. It targets RSV polymerase with an IC50 of 0.66 μM and impedes RSV mRNA synthesis throug...
T36440 GS-441524 tris-isobutyryl ester
GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with...
T37295 Ganglioside GM1 Asialo Mixture
Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aer...
T69014 Sekikaic Acid
Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µ...
T38297 Ribavirin-13C5 Ribavirin-13C5
Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a...
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