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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12774 | RSV-IN-1 | RSV | |
RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM. | |||
T61343 | RSV/IAV-IN-1 | ||
RSV/IAV-IN-1 (compound 14e) is a potent dual inhibitor of RSV/IAV with lower cytotoxicity compared to Ribavirin, suggesting promising potential for researching RSV and/or IAV infections [1]. | |||
T61217 | RSV-IN-3 | ||
RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1]. | |||
T60910 | RSV-IN-4 | ||
RSV-IN-4 (Compound 2) has anti-RSV activity with EC50 of 11.76 μM. RSV-IN-4 is a respiratory syncytial virus (RSV) and influenza virus A (IAV) dual inhibitor [1]. | |||
T61704 | RSV-IN-6 | ||
RSV-IN-6 (Compound 53) is a specific agent that effectively inhibits the respiratory syncytial virus (RSV) by targeting the M2-1 protein. It shows strong potency, with EC50 values of 4.4 μM and 1.3 μM against RSV-A and R... | |||
T79217 | RSV L-protein-IN-2 | RSV | |
RSV L-protein-IN-2 (Compound A), a noncompetitive inhibitor of the RSV polymerase (IC50: 4.5 μM), exhibits antiviral activity against long RSV strains (EC50: 1.3 μM) [1]. | |||
T61291 | RSV/IAV-IN-2 | ||
RSV/IAV-IN-2 (compound 14c) represents a powerful dual inhibitor of RSV/IAV, exhibiting lower cytotoxicity compared to the clinical drug Ribavirin. It holds promise for the research of RSV and/or IAV infections [1]. | |||
T79219 | RSV L-protein-IN-3 | RSV | |
RSV L-protein-IN-3 is an inhibitor of the wild-type RSV polymerase, exhibiting an IC50 of 10.4 μM and an EC50 of 2.1 μM (against RSV), and possesses lower cytotoxicity compared to the clinical agent Ribavirin [1]. | |||
T79220 | RSV L-protein-IN-4 | RSV | |
RSV L-protein-IN-4 (Compound C) is a noncompetitive inhibitor of the RSV polymerase with an IC50 of 0.88 μM. It demonstrates potent antiviral activity against RSV strains, with an EC50 of 0.25 μM [1]. | |||
T73370 | RSV-IN-7 | ||
RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) . | |||
T76752 | Motavizumab | ||
Motavizumab (MEDI-524) is a monoclonal antibody targeting the respiratory syncytial virus (RSV). It is utilized in research focused on RSV infections in high-risk infants [1]. | |||
T77027 | Gontivimab | ||
Gontivimab (ALX-0171; VR-465), a potent anti-RSV prefusion F protein nanobody, exhibits antiviral activity by reducing the RSV load in the nose and lung, with a dissociation constant (K D) of 0.113 nM [1]. | |||
T79221 | RSV L-protein-IN-5 | RSV | |
RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 μM. It targets RSV polymerase with an IC50 of 0.66 μM and impedes RSV mRNA synthesis throug... | |||
T36440 | GS-441524 tris-isobutyryl ester | ||
GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with... | |||
T37295 | Ganglioside GM1 Asialo Mixture | ||
Ganglioside GM1 asialo is a component of cellular lipid rafts and can be formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. Ganglioside GM1 asialo is a glycolipid receptor for P. aer... | |||
T69014 | Sekikaic Acid | ||
Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µ... | |||
T38297 | Ribavirin-13C5 | Ribavirin-13C5 | |
Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a... |